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Chemistry, Biological Activities, and Uses of Copaiba Oil Resins

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Gums, Resins and Latexes of Plant Origin

Part of the book series: Reference Series in Phytochemistry ((RSP))

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Abstract

Copaiba oils are oleoresins naturally produced and exuded from the tree trunk of several species of the Copaifera genus, a Leguminosae. Like all natural oleoresins, it has a volatile and a resinous portion. In the case of copaiba oils, these portions are comprised of sesquiterpenes and diterpenes, respectively. Among the main sesquiterpenes present in copaiba oils of some Copaifera species are caryophyllene, humulene, and their derivatives. These molecules have potent anti-inflammatory properties and are present in commercial herbal medicines, for example, from Cordia verbenacea. Caryophyllene is currently one of the most important substances in copaiba oils, as it has shown activity in several pharmacological models, including cannabinoid receptors of the CB2 type. The ancestral uses of copaiba oils by people from Latin America for different applications have been confirmed in pharmacological and biotechnological studies. Its importance as a natural bioactive product has grown exponentially, especially with the recent discoveries of the properties of caryophyllene.

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Acknowledgments

This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – Brasil (CAPES) – Finance Code 001. The authors would like to acknowledge the financial support of Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) and the National Council for Scientific and Technological Development (CNPq). The authors also acknowledge the Military Engineering Institute and the Federal University of Amazonas for their academic support.

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  1. Departamento de Química, Instituto de Ciências Exatas, Universidade Federal do Amazonas, Manaus, AM, Brazil

    Milena Campelo Freitas de Lima & Valdir F. da Veiga-Junior

  2. Departamento de Engenharia Química, Instituto Militar de Engenharia, Rio de Janeiro, RJ, Brazil

    Rayssa Ribeiro, Sthephanie Silva dos Santos Tavares, Yuri Campello Dias de Araujo & Valdir F. da Veiga-Junior

  3. Departamento de Ciências Biológicas, Instituto de Ciências Biológicas, Universidade Federal do Amazonas, Manaus, AM, Brazil

    Josiane Elizabeth Almeida e Silva

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  1. Department of Botany, Karnatak University, Dharwad, Karnataka, India

    Hosakatte Niranjana Murthy

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de Lima, M.C.F., Ribeiro, R., Almeida e Silva, J.E., dos Santos Tavares, S.S., de Araujo, Y.C.D., da Veiga-Junior, V.F. (2022). Chemistry, Biological Activities, and Uses of Copaiba Oil Resins. In: Murthy, H.N. (eds) Gums, Resins and Latexes of Plant Origin. Reference Series in Phytochemistry. Springer, Cham. https://doi.org/10.1007/978-3-030-76523-1_19-1

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