The Gallardo LP 560-4 was a significant update of the Gallardo, powered by a new, uneven firing 5.2 L (5,200 cc; 320 cu in) V10 engine that produces 560 PS (412 kW; 552 hp) at 8,000 rpm and 540 N⋅m (398 lb⋅ft) of torque at 6,500 rpm.
Featuring "Iniezione Diretta Stratificata" direct fuel injection system to improve efficiency; fuel consumption and CO2 emissions have been reduced by 18% despite the increase in performance. The car was redesigned, inspired by the Murciélago LP 640 and Reventón.