Young Barcelona midfielder Jonathan Dos Santos is the most notable player to miss out on the final selection. Defensive duo Juan Carlos Valenzuela (America) and Adrian Aldrete (Morelia) were the other two players to miss the cut.
"The Mexican Football Federation is grateful to Jonathan Dos Santos, Juan Carlos Valenzuela and Adrian Aldrete for their dedication, discipline, professionalism and commitment shown during the preparations with the national team," read a statement on the governing body's official website.
Mexico have been drawn in Group A alongside Uruguay, France and host nation South Africa, who they face in the curtain raiser in Johannesburg on June 11.
| Goalkeepers | - |
| Oscar Perez | Chiapas |
| Guillermo Ochoa | America |
| Luis Ernesto Michel | Guadalajara |
| Defenders | - |
| Rafael Marquez | Barcelona (ESP) |
| Ricardo Osorio | Stuttgart (GER) |
| Francisco Rodriguez | PSV Eindhoven (NED) |
| Carlos Salcido | PSV Eindhoven (NED) |
| Hector Moreno | AZ Alkmaar (NED) |
| Paul Aguilar | Pachuca |
| Efrain Juarez | Pumas UNAM |
| Jonny Magallon | Guadalajara |
| Joerge Torres Nilo | Atlas |
| Midfielders | - |
| Andres Guardado | Deportivo La Coruna |
| Giovani Dos Santos | Galatasaray (on loan from Tottenham Hotspur) |
| Gerrardo Torrado | Cruz Azul |
| Israel Castro | Pumas UNAM |
| Forwards | - |
| Pablo Barrera | Pumas UNAM |
| Adolfo Bautista | Guadalajara |
| Alberto Medina | Guadalajara |
| Cuauhtemoc Blanco | Veracruz |
| Carlos Vela | Arsenal (ENG) |
| Javier Hernandez | Manchester United (ENG) |
| Guillermo Franco | West Ham United (ENG) |
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